… CatB is normally located in lysosomes and plays a role in the autophagy … HeLa cells and
then explored the effects of PMBE on the expression of CatB. Our results proved that HeLa cells …

… involved in the apoptotic effect of PS extract. Changes in … cytotoxic effect of Pinus massoniana
bark extract (PMBE) was … sion of Bcl-2 was decreased in PMBE-treated HeLa cells. PMBE …

… massoniana extract on HeLa cells, demonstrating that cell cycle … Mitochondria play a critical
role in apoptosis, releasing … by altering Bcl-2 and Bax protein expression in A549 cells more …

… Involvement of the Bcl-2 family members in Pinus massoniana bark extract induced apoptosis
in HeLa cells. … Pinus massoniana bark extract selectively induces apoptosis in human …

… that maritime pine tannin extract can play a favorable role in cancer treatment, … of the Bcl-2
protein in MPTE-treated HeLa cells. … bark extracts such as the Pinus massoniana bark extract, …

… massoniana bark extract (PMBE) may induce the apoptosis of hepatoma and cervical cancer
cells. … In addition, PMBE is able to inhibit cell proliferation and induce apoptosis in human …

… massoniana bark also could inhibit the viability of HeLa cells … important role, since its excessive
accumulation in cancer cells … that prevent and promote apoptosis, such as Bcl-2 and Bax. …

… (Pe4) on HeLa cells had the highest inhibitory effect, and its IC … Bcl-2 gene expression, which
inhibits intracellular apoptosis [… bark had a greater inhibitory effect on the enzymes involved …

… Pinus massoniana bark extract … , the expressions of downstream Bcl-2 family and rapamycin
target proteins … Anthocyanins can target uPA and MMPs and thus play a role in inhibiting …

… cell signaling pathways involved in carcinogenesis such as … and the members of the Bcl-2
family of proteins including pro-… shown to induce apoptosis of malignant cells through different …